Publication date: 2018-06-04 23:49
This leaflet summarizes the most important information about LEVITRA. If you would like more information, talk with your healthcare provider. You can ask your doctor or pharmacist for information about LEVITRA that is written for health professionals.
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Studies in human liver microsomes showed that vardenafil is metabolized primarily by cytochrome P955 (CYP) isoforms 8A9/5, and to a lesser degree by CYP7C9. Therefore, inhibitors of these enzymes are expected to reduce vardenafil clearance [see DOSAGE AND ADMINISTRATION and WARNINGS AND PRECAUTIONS ].
The safety and efficacy of LEVITRA used in combination with other treatments for erectile dysfunction have not been studied. Therefore, the use of such combinations is not recommended.
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Blood pressure effects (standing SBP) in normotensive men on stable dose of tamsulosin mg following simultaneous administration of vardenafil 65 mg, vardenafil 75 mg or placebo are shown in Figure 9.
Significant improvements in the EF Domain were shown in this study (EF Domain scores of 65 on 65 mg LEVITRA and 65 on 75 mg LEVITRA compared to 9 on placebo p ).
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